University of California, Riverside

Graduate Medical Education

Clinical Faculty Biographies

Dr. Issa Alesh

Health Science Clinical Assistant Professor

Dr. Issa Alesh

Medical Office

St. Bernardine Medical Center
2102 N. Waterman Ave.,
San Bernardino, Calif. 92404
(909) 881-7400

Academic Office

School of Medicine
University of California, Riverside
Riverside, Calif. 92521
If you are a patient, please do not use this email address.
Contact the medical office by telephone.

Education and Training

  • Cardiology Fellowship, ACGME Accredited, Wayne State University/Detroit Medical Center, Detroit, Michigan
  • Heart Failure & Heart Transplant Fellowship, Henry Ford Hospital, Detroit, Michigan
  • Residency Internal Medicine, St. Joseph Mercy Oakland Hospital, Pontiac, Michigan
  • Externship, Cardiology Division at St. Vincent Hospital, New York, New York
  • Internship, Damascus University Hospital, Damascus, Syria
  • M.D., Damascus University School of Medicine, Damascus, Syria


Dr. Issa G. Alesh, M.D., F.A.C.C., R.P.V.I. is a current assistant clinical professor for the University of California, Riverside Cardiovascular Fellowship Program.

Alesh completed his M.D. and internship in Syria before coming to New York and Michigan to complete the rest of his training. He was also an attending cardiologist at the Detroit Receiving Hospital and Harper University Hospital in Michigan before becoming the attending cardiologist in the St. Bernardine Medical Center in California.

Prior to coming to UCR, Alesh was the assistant professor of internal medicine in the Division of Cardiology in Wayne State University, Detroit, Michigan. There, he was recognized as a key faculty member on the ACGME website and served on numerous committees, including the Department of Internal Medicine Compensation Advisory Committee.

Alesh is also involved in the American College of Cardiology as a fellow.

Research Interests

Alesh's current projects include an RV lead thrombus case report and literature review, interventricular lipomatous hypertrophy, and peri-partum cardiomypathy.

Other cardiology aspects include diastolic heart failure, cardio-oncology, echocardiography, and mitral regurgitation.

Selected Publications

  • Alesh I, Briasoulis A, Kamatam S, Afonso L. Lipomatous hypertrophy of the right ventricle and interventricular septum associated with ventricular arrhythmia. Int J Cardiovasc Imaging. 2016 Mar;32(3):449-50. doi: 10.1007/s10554-015-0781-0. Epub 2015 Sep 30.
  • Palla M, Briasoulis A, Siddiqui F, Alesh I, Afonso L. Long (>12 Months) and Short (<6 Months) Versus Standard Duration of Dual Antiplatelet Therapy After Coronary Stenting: A Systematic Review and Meta-Analysis. Am J Ther. 2015 Aug 11. [Epub ahead of print]
  • Afonso L, Briasoulis A, Mahajan N, Kondur A, Siddiqui F, Siddiqui S, Alesh I, Cardozo S, Kottam A. Comparison of right ventricular contractile abnormalities in hypertrophic cardiomyopathy versus hypertensive heart disease using two dimensional strain imaging: a cross-sectional study. Int J Cardiovasc Imaging. 2015 Dec;31(8):1503-9. doi: 10.1007/s10554-015-0722-y. Epub 2015 Aug 6.
  • Briasoulis A, Mallikethi-Reddy S, Palla M, Alesh I, Afonso L. Myocardial fibrosis on cardiac magnetic resonance and cardiac outcomes in hypertrophic cardiomyopathy: a meta-analysis. Heart. 2015 Sep;101(17):1406-11. doi: 10.1136/heartjnl-2015-307682. Epub 2015 Jun 9. Review.
  • Cardozo S, Gunasekaran P, Patel H, McGorisk T, Toosi M, Faraz H, Zalawadiya S, Alesh I, Kottam A, Alfonso L. Is bacteriostatic saline superior to normal saline as an echocardiographic contrast agent? Int J Cardiovasc Imaging. 2014 Dec;30(8):1483-9. doi: 10.1007/s10554-014-0493-x. Epub 2014 Jul 15.
  • Ference B, Yoo W, Alesh I, Mahajan N*, Mirowska K*, Mewada A*, Kahn J, Afonso L, Williams K, Flack J: Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease: A Mendelian Randomization Analysis. J Am Coll Cardiol. 2012 Dec 25;60(25):2631-9.
  • Rastogi S, Mishra S, Zaca V, Alesh I, Gupta RC, Goldstein S, Sabbah HN. Effect of long-term monotherapy with the aldosterone receptor blocker eplerenone on cytoskeletal proteins and matrix metalloprotienases in dogs with heart failure. Cardiovasc Drugs Ther. 2007 Dec;21(6):415-22.
  • Alesh I, Kayali F, Stein PD: Catheter-Directed Thrombolysis (Intra-Thrombus Injection) in Treatment of Deep Venous Thrombosis: A Systematic Review. Catheter Cardiovasc Interv. 2007 Jul 1;70(1):143-8. Review
  • Beemath A, Stein PD, Skaf E, Al Sibae R, Alesh I: Risk of Venous Thromboembolism in Patients Hospitalized with Heart Failure. Am J Cardiol 2006 Sep 15;98(6):793-5. Epub 2006 Jul 28.
  • Stein PD, Beemath A, Skaf E, Kayali F, Janjua M, Alesh I, Olson RE: Usefulness of 4-, 8- and 16-Slice Computed Tomography for Detection of Graft Occlusion or Patency after Coronary Artery Bypass Grafting. Am J of Cardiol. 2005 Dec 15;96(12):1669-73
  • Stein PD, Kayali F, Beemath A, Skaf E, Alnas M, Alesh I, Olson RE: Mortality from Acute Pulmonary Embolism According to Season. Chest. 2005 Nov;128(5):3156-8

More Information 

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

Department Information

Graduate Medical Education
2608 School of Medicine Education Building

Tel: (951) 827-7669